[1-Benzyl-7-(2-aminoethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester → [1-Benzyl-7-(2-aminoethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid

HRID 2301982Notes

Reaction equation

HRID 2301982 reaction equation
FC(F)(F)C(O)=O.COC(=O)CC1CC2C(=CC(OCCCCNC(N)=N)=CC=2)NC1=O.C[O:34][C:35](=[O:59])[CH2:36][C:37]1[C:38](=[O:58])[N:39]([CH2:51][C:52]2[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=2)[C:40]2[C:45]([CH:46]=1)=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][NH2:50])[CH:41]=2>>[CH2:51]([N:39]1[C:40]2[C:45](=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][NH2:50])[CH:41]=2)[CH:46]=[C:37]([CH2:36][C:35]([OH:59])=[O:34])[C:38]1=[O:58])[C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=1

Participants

3

Reactant 2

HCID 69979287[1-Benzyl-7-(2-aminoethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl EsterHCID 178499385HCID 178499385, compound

Product 1

HCID 18462562[1-Benzyl-7-(2-aminoethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid

Procedure

The title compound is prepared according to the procedure of Example 84 except that [7-(4-guanidino-butoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester trifluoroacetate is replaced with [l-benzyl-7-(2-aminoethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

Sources & evidence

ORD record
ord-21575fdb13cf41d5a75fda9b2fc7ede8
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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