HCID 178462958, compound → HCID 178462953, compound

HRID 2301988Notes

Reaction equation

HRID 2301988 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].COC(=O)CC1CC2C(=CC(OCCCCNC(N)=N)=CC=2)NC1=O.C[O:34][C:35](=[O:58])[CH2:36][C:37]1[C:38](=[O:57])[N:39]([CH2:55][CH3:56])[C:40]2[C:45]([CH:46]=1)=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][NH:51][C:52]([NH2:54])=[NH:53])[CH:41]=2>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH2:55]([N:39]1[C:40]2[C:45](=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][NH:51][C:52]([NH2:54])=[NH:53])[CH:41]=2)[CH:46]=[C:37]([CH2:36][C:35]([OH:58])=[O:34])[C:38]1=[O:57])[CH3:56]

Participants

3

Reactant 2

HCID 178462958HCID 178462958, compoundHCID 178499385HCID 178499385, compound

Product 1

HCID 178462953HCID 178462953, compound

Procedure

The title compound was prepared using the procedure of Example 84 except that [7-(4-guanidino-butoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic acid methyl ester trifluoroacetate was replaced with [1-ethyl-7-(3-guanidino-propoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]-acetic acid methyl ester.

Sources & evidence

ORD record
ord-23a51145a94e48c9ac990823c6572cae
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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