HCID 178462957, compound → HCID 178462950, compound

HRID 2301989Notes

Reaction equation

HRID 2301989 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].COC(=O)CC1CC2C(=CC(OCCCCNC(N)=N)=CC=2)NC1=O.C[O:34][C:35](=[O:59])[CH2:36][C:37]1[C:38](=[O:58])[N:39]([CH2:56][CH3:57])[C:40]2[C:45]([CH:46]=1)=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][CH2:51][NH:52][C:53]([NH2:55])=[NH:54])[CH:41]=2>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH2:56]([N:39]1[C:40]2[C:45](=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][CH2:51][NH:52][C:53]([NH2:55])=[NH:54])[CH:41]=2)[CH:46]=[C:37]([CH2:36][C:35]([OH:59])=[O:34])[C:38]1=[O:58])[CH3:57]

Participants

3

Reactant 2

HCID 178462957HCID 178462957, compoundHCID 178499385HCID 178499385, compound

Product 1

HCID 178462950HCID 178462950, compound

Procedure

The title compound is prepared using the procedure of Example 84 except that [7-(4-guanidino-butoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic acid methyl ester trifluoroacetate is replaced with [1-ethyl-7-(4-guanidino-butoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

Sources & evidence

ORD record
ord-02d598d1a8f6473c9a2933043d4e56b3
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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