HCID 178499385, compound → HCID 178512975, compound

HRID 2301992Notes

Reaction equation

HRID 2301992 reaction equation
FC(F)(F)C(O)=O.COC(=O)CC1CC2C(=CC(OCCCCNC(N)=N)=CC=2)NC1=O.C[O:34][C:35](=[O:64])[CH2:36][C:37]1[C:38](=[O:63])[N:39]([CH2:56][C:57]2[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=2)[C:40]2[C:45]([CH:46]=1)=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][CH2:51][NH:52][C:53]([NH2:55])=[NH:54])[CH:41]=2>>[CH2:56]([N:39]1[C:40]2[C:45](=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][CH2:51][NH:52][C:53]([NH2:55])=[NH:54])[CH:41]=2)[CH:46]=[C:37]([CH2:36][C:35]([OH:64])=[O:34])[C:38]1=[O:63])[C:57]1[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=1

Participants

3

Reactant 2

HCID 178499385HCID 178499385, compoundHCID 178499386HCID 178499386, compound

Product 1

HCID 178512975HCID 178512975, compound

Procedure

The title compound is prepared according to the procedure of Example 84 except that [7-(4-guanidino-butoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic acid methyl ester trifluoroacetate is replaced with [1-benzyl-7-(4-guanidino-butoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

Sources & evidence

ORD record
ord-53571434d11d4990a50ba2ef1ec7d6db
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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