HCID 178462953, compound → HCID 178462956, compound

HRID 2301994Notes

Reaction equation

[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].C(N1C2C(=CC=C(OCCCNC(N)=N)C=2)C=C(CC(O)=O)C1=O)C.FC(F)(F)C(O)=O.[CH2:40]([N:42]1[C:51]2[C:46](=[CH:47][CH:48]=[C:49]([O:52][CH2:53][CH2:54][NH:55][C:56]([NH2:58])=[NH:57])[CH:50]=2)[CH:45]=[C:44]([CH2:59][C:60]([OH:62])=[O:61])[C:43]1=[O:63])[CH3:41]>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH2:40]([N:42]1[C:51]2[C:46](=[CH:47][CH:48]=[C:49]([O:52][CH2:53][CH2:54][NH:55][C:56]([NH2:58])=[NH:57])[CH:50]=2)[CH2:45][CH:44]([CH2:59][C:60]([OH:62])=[O:61])[C:43]1=[O:63])[CH3:41]

Participants

Reactant 2

HCID 178462953HCID 178462953, compound

HCID 178462955HCID 178462955, compound

Product 1

HCID 178462956HCID 178462956, compound

Procedure

The title compound is prepared using the procedure of Example 158 except that [1-ethyl-7-(3-guanidino-propoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid trifluoroacetate is replaced with [1-ethyl-7-(2-guanidino-ethoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid trifluoroacetate.

Sources & evidence

ORD record: ord-eaf426b465884389b7578decfd0e1b41
Source dataset: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06429214B1

Reaction notes

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