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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2301997Generated: October 30, 2026

tert-butyl N-(3-bromopropyl)carbamate → [7-(3-tert-Butoxycarbonylaminopropoxy)-1-benzyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic Acid Methyl Ester

https://huagongshe.com/reaction/2301997

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(3-bromopropyl)carbamateHCID 4460490—
Reactant(1-Benzyl-7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl esterHCID 69979518—
SolventAcetic AcidHCID 176—
Product[7-(3-tert-Butoxycarbonylaminopropoxy)-1-benzyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic Acid Methyl EsterHCID 69979340—

Reaction Steps

The title compound is prepared using the procedure of Example 75 and (1-benzyl-7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl ester in place of 7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)acetic acid and (3-bromopropyl)carbamic acid tert-butyl ester in place of (2-bromoethyl)carbamic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06429214B1
Source datasetuspto-grants-2002_08
ORD IDord-e01dfe6192764524b9461c8b56050f8b
Source noteuspto-grants-2002_08