HCID 178499385, compound → HCID 178512985, compound

HRID 2302001Notes

Reaction equation

HRID 2302001 reaction equation
FC(F)(F)C(O)=O.COC(=O)CC1CC2C(=CC(OCCCCNC(N)=N)=CC=2)NC1=O.C[O:34][C:35](=[O:63])[CH2:36][CH:37]1[CH2:46][C:45]2[C:40](=[CH:41][C:42]([O:47][CH2:48][CH2:49][CH2:50][NH:51][C:52]([NH2:54])=[NH:53])=[CH:43][CH:44]=2)[N:39]([CH2:55][C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)[C:38]1=[O:62]>>[CH2:55]([N:39]1[C:40]2[C:45](=[CH:44][CH:43]=[C:42]([O:47][CH2:48][CH2:49][CH2:50][NH:51][C:52]([NH2:54])=[NH:53])[CH:41]=2)[CH2:46][CH:37]([CH2:36][C:35]([OH:63])=[O:34])[C:38]1=[O:62])[C:56]1[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=1

Participants

3

Reactant 2

HCID 178499385HCID 178499385, compoundHCID 178499391HCID 178499391, compound

Product 1

HCID 178512985HCID 178512985, compound

Procedure

The title compound was prepared according to the procedure of Example 84 except that [7-(4-guanidino-butoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]acetic acid methyl ester trifluoroacetate was replaced with [1-benzyl-7-(3-guanidino-propoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester.

Sources & evidence

ORD record
ord-db9c77f7c34b4c5b97ea4ed7c0ba91c9
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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