tert-butyl N-(4-bromobutyl)carbamate → HCID 69979254, compound

HRID 2302002Notes

Reaction equation

HRID 2302002 reaction equation
[C:1]([O:5][C:6](=[O:13])[NH:7][CH2:8][CH2:9][CH2:10][CH2:11]Br)([CH3:4])([CH3:3])[CH3:2].[CH3:14][O:15][C:16](=[O:30])[CH2:17][C:18]1[C:19](=[O:29])[NH:20][C:21]2[C:26]([CH:27]=1)=[CH:25][CH:24]=[C:23]([OH:28])[CH:22]=2>>[CH3:14][O:15][C:16](=[O:30])[CH2:17][C:18]1[C:19](=[O:29])[NH:20][C:21]2[C:26]([CH:27]=1)=[CH:25][CH:24]=[C:23]([O:28][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:13])[CH:22]=2

Participants

3

Reactant 2

HCID 10868765tert-butyl N-(4-bromobutyl)carbamateHCID 69978072HCID 69978072, compound

Product 1

HCID 69979254HCID 69979254, compound

Procedure

The title compound is prepared according to the procedure of Example 75 except that (4-bromobutyl)-carbamic acid tert-butyl ester is used in place of (3-bromopropyl)-carbamic acid tert-butyl ester and that (7-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid methyl ester is used in place of (7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl ester.

Sources & evidence

ORD record
ord-ab51cb9a2ef8465fade95d1567af9812
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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