tert-butyl N-(3-bromopropyl)carbamate → HCID 69978227, compound

HRID 2302003Notes

Reaction equation

HRID 2302003 reaction equation
[C:1]([O:5][C:6](=[O:12])[NH:7][CH2:8][CH2:9][CH2:10]Br)([CH3:4])([CH3:3])[CH3:2].[CH3:13][O:14][C:15](=[O:29])[CH2:16][C:17]1[C:18](=[O:28])[NH:19][C:20]2[C:25]([CH:26]=1)=[CH:24][CH:23]=[C:22]([OH:27])[CH:21]=2>>[CH3:13][O:14][C:15](=[O:29])[CH2:16][C:17]1[C:18](=[O:28])[NH:19][C:20]2[C:25]([CH:26]=1)=[CH:24][CH:23]=[C:22]([O:27][CH2:10][CH2:9][CH2:8][NH:7][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:12])[CH:21]=2

Participants

3

Reactant 2

HCID 4460490tert-butyl N-(3-bromopropyl)carbamateHCID 69978072HCID 69978072, compound

Product 1

HCID 69978227HCID 69978227, compound

Procedure

The title compound is prepared according to the procedure of Example 75 except that (3-bromopropyl)-carbamic acid tert-butyl ester is used in place of (2-bromoethyl)-carbamic acid tert-butyl ester and that (7-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid methyl ester is used in place of (7-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-acetic acid methyl ester.

Sources & evidence

ORD record
ord-2f70372211b54b1aa32c14a40c108d81
Source dataset
uspto-grants-2002_08
Patent number
US06429214B1

Reaction notes

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