反应详情

2-Quinoxaloyl chloride (0.84 g, 4.4 mmol) was added to a solution of 1-adamantanamine (0.60 g, 4.0 mmol) in pyridine (10 mL). The reaction was then stirred for 30 min. To the stirring reaction mixture was added water (100 mL) which caused the product to precipitate. This precipitate was filtered, washed with water (3×25 mL), and dried under high vacuum for 16 h. This provided 1.00 g (82%) of (91):

1. customTo the stirring reaction mixture
2. customto precipitate
3. filtrationThis precipitate was filtered
4. washwashed with water (3×25 mL)
5. customdried under high vacuum for 16 h