Pyridine → HCID 22136418, compound

HRID 2302041Notes

Reaction equation

HRID 2302041 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[C:11](Cl)=[O:12].[NH2:14][CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16]1.N1C=CC=CC=1>O>[CH2:16]1[C:17]2[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:23][CH:15]1[NH:14][C:11]([C:2]1[CH:3]=[N:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:1]=1)=[O:12]

Participants

5

Reactant 3

HCID 1049PyridineHCID 763102-AminoindaneHCID 2734681Quinoxaline-2-carbonyl chloride

Product 1

HCID 22136418HCID 22136418, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Prepared from 2-quinoxaloyl chloride (0.32 g, 1.7 mmol), 2-aminoindan (0.20 g, 1.5 mmol), pyridine (3 mL), and water (30 mL) yielding 0.23 g (53%) of (221):

Sources & evidence

ORD record
ord-8999e0ac207b4d96bf8549197e4edf79
Source dataset
uspto-grants-2002_08
Patent number
US06429207B1

Reaction notes

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