Pyridine → HCID 22136387, compound

HRID 2302042Notes

Reaction equation

HRID 2302042 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[C:11](Cl)=[O:12].[CH:14]1([NH2:22])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1.N1C=CC=CC=1>O>[CH:14]1([NH:22][C:11]([C:2]2[CH:3]=[N:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[N:1]=2)=[O:12])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

5

Reactant 3

HCID 1049PyridineHCID 2903CyclooctylamineHCID 2734681Quinoxaline-2-carbonyl chloride

Product 1

HCID 22136387HCID 22136387, compoundYield 39.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Prepared from 2-quinoxaloyl chloride (193 mg, 1.0 mmol), cyclooctylamine (123 μL, 114 mg, 0.90 mmol), pyridine (5 mL), and water (100 mL) yielding 100 mg (39%) of (228):

Sources & evidence

ORD record
ord-e3dc04a6313648ccb8a9006c74dd97c0
Source dataset
uspto-grants-2002_08
Patent number
US06429207B1

Reaction notes

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