HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 178461307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 178461358 | HCID 178461358 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178461307 | HCID 178461307 | — |
Reaction Steps
4-Hydroxy-8-trifluoromethyl-3-carboxylic acid (514 mg, 2 mmol), thionyl chloride, trans-4-methylcyclohexylamine hydrochloride (225 mg, 1.5 mmol), and triethylamine (2 mL) afforded crude N-(trans-4-methylcyclohexyl)-4-chloro-8-trifluoromethylquinoline-3-carboxamide:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06429207B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-0239406441b34d5a93fcc42731ad098f |
| Source note | uspto-grants-2002_08 |