Hydrochloric Acid → HCID 15279121, compound

Participants

Reaction Steps

To the obtained 1-(1-cyano-1-hydroxyethyl) adamantane were added phosphorus oxychloride three times as much as the moles of the adamantane derivative, and170 ml of dried pyridine, and the resultant mixture was refluxed for 2 hours. Ether was added to the reaction mixture to a volume of 600 ml, and to this solution was added cooled 4N-hydrochloric acid (600 g) with stirring. The obtained organic layer was concentrated to give 17.4 g of 1-(1-cyanoethenyl)adamantane.

Provenance & Evidence