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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2302124Generated: October 27, 2026

(+-)-Cyclohexylphenylglycolic acid → N-Desethyloxybutynin

https://huagongshe.com/reaction/2302124

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-Cyclohexylphenylglycolic acidHCID 97700—
Reactant4-Ethylamino-2-butynyl chlorideHCID 18459506—
ProductN-DesethyloxybutyninHCID 133577—

Reaction Steps

by standard esterification technique, reacting cyclohexylphenyl glycolic acid with 4-ethylamino-2-butynyl chloride to produce 4-ethylamino-2-butynyl cyclohexylphenyl-glycolate (DEO).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432446B1
Source datasetuspto-grants-2002_08
ORD IDord-89277cc64fd14c4e9fd29ee6f4154367
Source noteuspto-grants-2002_08