HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-(4-Methoxyphenyl)-1,1-dimethylethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 1-Methyl-4-(2-methyl-2-nitropropyl)benzene | HCID 12696804 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | 2-(4-Methoxyphenyl)-1,1-dimethylethylamine | HCID 91892 | — |
Reaction Steps
The 1-(4-methylphenyl)-2-methyl-2-nitropropane (1.3 g) was hydrogenated for 5 hours at 65 p.s.i. hydrogen in ethanol (30 mL) using 1.4 g of Raney nickel as catalyst. Removal of the catalyst by filtration and evaporation of the solvent yielded 1.15 g of 1,1-dimethyl-2-(4-methoxyphenyl)ethylamine as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432656B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-b6ce9e958be945119df15bd49ef620b2 |
| Source note | uspto-grants-2002_08 |