N-[2-Hydroxy-3-(4-chlorophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride → N-[2-Hydroxy-3-(3-ethylphenoxy)propyl)-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

HRID 2302198Notes

Reaction equation

HRID 2302198 reaction equation
Cl.[OH:2][CH:3]([CH2:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][CH:21]=1)[CH2:4][NH:5][C:6]([CH3:17])([CH3:16])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1.Cl.O[CH:29](COC1C=CC(C(C)(C)C)=CC=1)[CH2:30]NC(C)(C)CC1C=CC(OC)=CC=1>>[ClH:26].[OH:2][CH:3]([CH2:18][O:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH2:29][CH3:30])[CH:21]=1)[CH2:4][NH:5][C:6]([CH3:17])([CH3:16])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 18459608N-[2-Hydroxy-3-(4-chlorophenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride2×HCID 22640914N-[2-Hydroxy-3-(4-t-butylphenoxy)propyl]-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride2×

Product 1

HCID 22640833N-[2-Hydroxy-3-(3-ethylphenoxy)propyl)-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine Hydrochloride

Procedure

GC/EI-MS, m/z (rel. int.) 342 (M−15,0.6), 237(16), 236 (100), 163 (5), 121 (21), 114 (6), 105 (5), 90 (6).

Sources & evidence

ORD record
ord-a9a22ab671f9424e8ded937395fa6892
Source dataset
uspto-grants-2002_08
Patent number
US06432656B1

Reaction notes

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