2-Thiopheneglyoxylic acid → HCID 21083675, compound

HRID 230221Notes

Reaction equation

HRID 230221 reaction equation
[O:1]1[C:5]2[CH:6]=[C:7]([NH2:11])[C:8]([NH2:10])=[CH:9][C:4]=2[O:3][CH2:2]1.[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17](=O)[C:18](O)=[O:19]>>[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17]1[C:18](=[O:19])[NH:10][C:8]2[CH:9]=[C:4]3[O:3][CH2:2][O:1][C:5]3=[CH:6][C:7]=2[N:11]=1

Participants

3

Reactant 2

HCID 776942-Thiopheneglyoxylic acidHCID 30807881,2-Diamino-4,5-methylenedioxybenzene

Product 1

HCID 21083675HCID 21083675, compound

Procedure

The quinoxalin-2-one of the present example is prepared with Benzo[1,3]dioxole-5,6-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 7-thiophen-2-yl-5H-1,3-dioxa-5,8-diaza-cyclopenta[b]naphthalen-6-one.

Sources & evidence

ORD record
ord-5621fd11a527478b8861d825febc04b7
Source dataset
uspto-grants-2009_07
Patent number
US07566719B2

Reaction notes

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