2-Thiopheneglyoxylic acid → HCID 21083666, compound

HRID 230222Notes

Reaction equation

HRID 230222 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([NH2:12])[C:8]([NH2:11])=[CH:9][CH:10]=1)(=[O:4])=[O:3].[S:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[C:18](=O)[C:19](O)=[O:20]>>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]2[C:8](=[CH:9][CH:10]=1)[NH:11][C:19](=[O:20])[C:18]([C:14]1[S:13][CH:17]=[CH:16][CH:15]=1)=[N:12]2)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 776942-Thiopheneglyoxylic acidHCID 69514184-(methylsulfonyl)benzene-1,2-diamine

Product 1

HCID 21083666HCID 21083666, compound

Procedure

The quinoxalin-2-one of the present example is prepared with 4-Methanesulfonyl-benzene-1,2-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Methanesulfonyl-3-thiophen-2-yl-1H-quinoxalin-2-one.

Sources & evidence

ORD record
ord-1385a04093fd4ebf96284dc9db6961bf
Source dataset
uspto-grants-2009_07
Patent number
US07566719B2

Reaction notes

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