HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Morpholinobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-(Morpholin-4-yl)benzoic acid | HCID 2795549 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Morpholinobenzoyl chloride | HCID 22057972 | — |
Reaction Steps
Oxalyl chloride (0.14 ml) was added to a solution of 3-morpholinobenzoic acid (0.28 g) in methylene chloride (10 ml) which contained DMF (2 drops). The reaction mixture was stirred for 18 hours at ambient temperature. The mixture was evaporated and azeotroped with toluene to give 3-morpholinobenzoyl chloride (0.3 g); Mass Spectrum: M+H+ 222.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432949B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-de1b5ea8f07d4740b8be2bada7ab6b96 |
| Source note | uspto-grants-2002_08 |