HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinoyl Chloride → HCID 22057946, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Reactant | N-(3-amino-4-methylphenyl)-2-morpholinopyridine-4-carboxamide | HCID 17904941 | — |
| Product | HCID 22057946 | HCID 22057946 | 56% |
Reaction Steps
Using an analogous procedure to that described in Example 17, 6-chloropyridine-3-carbonyl chloride was reacted with N-(3-amino4methylphenyl)-2-morpholinopyridine-4-carboxamide to give the title compound in 56% yield; NMR Spectrum: (DMSOd6): 2.21 (s, 3.53 (m, 4H), 3.69-3.73 (m, 4H), 7.08 (d, 1H), 7.25 (d, 2H), 7.56 (d, 1H) 7.69 (d, 1H), 7.82 (d, 1H), 8.26 (d, 1H), 8.37 (d, 1H), 8.96 (d, 1H); Mass Spectrum M+H+ 452 and 454 .
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432949B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-b0a59bf70f7749d998eea0d4828ccf63 |
| Source note | uspto-grants-2002_08 |