4-Bromo-2-nitroaniline → HCID 21083662, compound

HRID 230233Notes

Reaction equation

HRID 230233 reaction equation
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([N+:9]([O-])=O)[CH:3]=1.[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17](=O)[C:18](O)=[O:19]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:7][CH:8]=1)[NH:6][C:18](=[O:19])[C:17]([C:13]1[S:12][CH:16]=[CH:15][CH:14]=1)=[N:9]2

Participants

3

Reactant 2

HCID 701324-Bromo-2-nitroanilineHCID 776942-Thiopheneglyoxylic acid

Product 1

HCID 21083662HCID 21083662, compound

Procedure

The quinoxalin-2-one of the present example is prepared with 4-bromo-2-nitroaniline and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-bromo-3-thiophen-2-yl-1H-quinoxalin-2-one.

Sources & evidence

ORD record
ord-71a1277384f54f7bb5c27cc82a659754
Source dataset
uspto-grants-2009_07
Patent number
US07566719B2

Reaction notes

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