Veratrylamine → 2-Chloro-6-nitro-4-(3,4-dimethoxybenzylamino)-thieno-[2,3-d]-pyrimidine

HRID 2302344Notes

Reaction equation

HRID 2302344 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[CH2:6][NH2:7].[Cl:13][C:14]1[N:15]=[C:16](Cl)[C:17]2[CH:22]=[C:21]([N+:23]([O-:25])=[O:24])[S:20][C:18]=2[N:19]=1>>[Cl:13][C:14]1[N:15]=[C:16]([NH:7][CH2:6][C:5]2[CH:8]=[CH:9][C:10]([O:11][CH3:12])=[C:3]([O:2][CH3:1])[CH:4]=2)[C:17]2[CH:22]=[C:21]([N+:23]([O-:25])=[O:24])[S:20][C:18]=2[N:19]=1

Participants

3

Reactant 2

HCID 79832VeratrylamineHCID 18460040HCID 18460040, compound

Product 1

HCID 184604582-Chloro-6-nitro-4-(3,4-dimethoxybenzylamino)-thieno-[2,3-d]-pyrimidine

Procedure

Following the procedure of Example 1, the reaction of 3,4-dimethoxybenzylamine with 2,4dichloro-6-nitro-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-nitro-4-(3,4-dimethoxybenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-031d11594bd24694a36345dca2021ea8
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

Loading…