Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2302354Generated: November 3, 2026

4-Fluorobenzylamine → 2,4-Dichloro-5-methylthieno(2,3-d)pyrimidine

https://huagongshe.com/reaction/2302354

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzylamineHCID 67326—
Reactant2,4-Dichloro-6-methylthieno[2,3-D]pyrimidineHCID 11106847—
Product2,4-Dichloro-5-methylthieno(2,3-d)pyrimidineHCID 12225299—
Product2-Chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidineHCID 18460383—

Reaction Steps

Following the procedure of Example 1, the reaction of 4-fluorobenzylamine with 2,4-dichloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine with 2,4-dichloro-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-5-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432950B1
Source datasetuspto-grants-2002_08
ORD IDord-754bcba7deab44dfa54f378d27e6a47e
Source noteuspto-grants-2002_08