4-Fluorobenzylamine → HCID 54304902, compound

HRID 2302360Notes

Reaction equation

HRID 2302360 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[Cl:10][C:11]1[N:12]=[C:13](Cl)[C:14]2[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[S:17][C:15]=2[N:16]=1>>[Cl:10][C:11]1[N:12]=[C:13]([NH:7][CH2:6][C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)[C:14]2[CH:19]=[C:18]([C:20]([F:22])([F:23])[F:21])[S:17][C:15]=2[N:16]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 18459967HCID 18459967, compound

Product 1

HCID 54304902HCID 54304902, compound

Procedure

Following the procedure of Example 1, the reaction of 4-fluorobenzylamine with 2,4-dichloro-6-trifluoromethyl-thieno-[2,3-d ]-pyrimidine yields 2-chloro-6-trifluoromethyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-d7d51835f66a47b394455f559f297ce4
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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