Benzenemethanamine, 3,4-dichloro- → HCID 18459993, compound

HRID 2302363Notes

Reaction equation

HRID 2302363 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].[Cl:11][C:12]1[N:13]=[C:14](Cl)[C:15]2[C:20]3[CH2:21][CH2:22][CH2:23][CH2:24][C:19]=3[S:18][C:16]=2[N:17]=1>>[Cl:11][C:12]1[N:13]=[C:14]([NH:6][CH2:5][C:4]2[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=2)[C:15]2[C:20]3[CH2:21][CH2:22][CH2:23][CH2:24][C:19]=3[S:18][C:16]=2[N:17]=1

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 2902342,4-Dichloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

Product 1

HCID 18459993HCID 18459993, compound

Procedure

Following the procedure of Example 1, the reaction of 3,4-dichlorobenzylamine with 2,4-dichloro-5,6,7,8-tetrahydro-[1]-benzothieno-[2,3-d]-pyrimidine yields 2-chloro-5,6,7,8-tetrahydro-4-(3,4-dichlorobenzylamino)-[1]-benzothieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-1aedb9044e9445269a1dfb9db6d668e2
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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