1,3-Benzodioxole-5-ethanamine → 2-Chloro-5,6-dimethyl-4-(3,4-methylenedioxyphenethylamino)-thieno-[2,3-d]-pyrimidine

HRID 2302383Notes

Reaction equation

HRID 2302383 reaction equation
[CH2:1]1[O:12][C:11]2[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][C:3]=2[O:2]1.[Cl:13][C:14]1[N:15]=[C:16](Cl)[C:17]2[C:22]([CH3:23])=[C:21]([CH3:24])[S:20][C:18]=2[N:19]=1>>[Cl:13][C:14]1[N:15]=[C:16]([NH:8][CH2:7][CH2:6][C:5]2[CH:9]=[CH:10][C:11]3[O:12][CH2:1][O:2][C:3]=3[CH:4]=2)[C:17]2[C:22]([CH3:23])=[C:21]([CH3:24])[S:20][C:18]=2[N:19]=1

Participants

3

Reactant 2

HCID 738741,3-Benzodioxole-5-ethanamineHCID 3645909HCID 3645909, compound

Product 1

HCID 184601022-Chloro-5,6-dimethyl-4-(3,4-methylenedioxyphenethylamino)-thieno-[2,3-d]-pyrimidine

Procedure

Following the procedure of Example 1, the reaction of 3,4-methylenedioxyphenethylamine with 2,4-dichloro-5,6-dimethyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-5,6-dimethyl-4-(3,4-methylenedioxyphenethylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-cc98a74adf6f4678aec9f88437a5e7cb
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

Loading…