Imidazole → HCID 18460031, compound

HRID 2302415Notes

Reaction equation

HRID 2302415 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Cl[C:7]1[N:8]=[C:9]([NH:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=2)[C:10]2[CH:15]=[C:14]([CH3:16])[S:13][C:11]=2[N:12]=1>>[N:1]1([C:7]2[N:8]=[C:9]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[C:10]3[CH:15]=[C:14]([CH3:16])[S:13][C:11]=3[N:12]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 184603832-Chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18460031HCID 18460031, compound

Procedure

Following the procedure of Example 97, the reaction of imidazole with 2-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(imidazol-1- yl)-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-3e6d068ece7144428dbde824cc8e1507
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

Loading…