Imidazole → HCID 23330410, compound

HRID 2302416Notes

Reaction equation

HRID 2302416 reaction equation
N1C=CN=C1.Cl[C:7]1[N:8]=[C:9](NCC2C=CC(F)=CC=2)[C:10]2[C:15]3[CH2:16][CH2:17][CH2:18][CH2:19][C:14]=3[S:13][C:11]=2[N:12]=1>>[N:12]1[C:11]2[S:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[C:10]=2[CH:9]=[N:8][CH:7]=1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 18460274HCID 18460274, compound

Product 1

HCID 23330410HCID 23330410, compound

Procedure

Following the procedure of Example 97, the reaction of imidazole with 2-chloro-5,6,7,8-tetrahydro-4-(4-fluorobenzylamino)-[1]-benzothieno-[2,3-d]-pyrimidine gives 2-(imidazol-1-yl)-5,6,7,8-tetrahydro-4-(4-fluorobenzylamino)-[1-benzothieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-f722a6acfac042e980f0789369fe4161
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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