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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2302696Generated: November 2, 2026

4-Cyanopyridine → HCID 18460504, compound

https://huagongshe.com/reaction/2302696

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-CyanopyridineHCID 7506—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 18459926HCID 18459926—
ProductHCID 18460504HCID 18460504—

Reaction Steps

With the procedure of Example 477, the reaction of 4-cyanopyridine and 2-amino-4-chloro-5-methyl-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(pyridin-4-yl)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432950B1
Source datasetuspto-grants-2002_08
ORD IDord-d84779d48b934414be139661b3fe9615
Source noteuspto-grants-2002_08