HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine → 2-(Pyridin-3-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine | HCID 18460014 | — |
| Reactant | 4-Fluoro-4-fluorobenzylamine | HCID 70144286 | — |
| Product | 2-(Pyridin-3-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine | HCID 18460358 | — |
Reaction Steps
With the procedure of Example 1, the reaction of 4-fluoro-4-fluorobenzylamine with 4-chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-3-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432950B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-83667c5fd08e4cd0a5d51d734ab3b02d |
| Source note | uspto-grants-2002_08 |