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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2302798Generated: October 29, 2026

4-Fluorobenzylamine → 2-(Pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine

https://huagongshe.com/reaction/2302798

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzylamineHCID 67326—
Reactant4-Chloro-2-(pyrazin-2-yl)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidineHCID 18460489—
Product2-(Pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidineHCID 18459937—

Reaction Steps

With the procedure of Example 1, the reaction of 4-fluorobenzylamine with 4-chloro-2-(pyrazin-2-yl)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432950B1
Source datasetuspto-grants-2002_08
ORD IDord-301eba6e48904c58aba2e37004677fd5
Source noteuspto-grants-2002_08