Benzenemethanamine, 3,4-dichloro- → HCID 18460090, compound

HRID 2302885Notes

Reaction equation

HRID 2302885 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].Cl[C:12]1[C:13]2[C:26]([Cl:27])=[C:25]([CH3:28])[S:24][C:14]=2[N:15]=[C:16]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=2)[N:17]=1>>[N:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[C:16]1[N:17]=[C:12]([NH:6][CH2:5][C:4]2[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=2)[C:13]2[C:26]([Cl:27])=[C:25]([CH3:28])[S:24][C:14]=2[N:15]=1

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 18460480HCID 18460480, compound

Product 1

HCID 18460090HCID 18460090, compound

Procedure

With the procedure of Example 1, the reaction of 3,4-dichlorobenzylamine with 4-chloro-2-(pyridin-2-yl)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-2-yl)-4-(3,4-dichlorobenzylamino)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-296d3ff170174bdfad4122ad6225bee3
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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