1,3-Benzodioxole-5-ethanamine → 2-(Pyridin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-5-methyl-thieno-[2,3-d]-pyrimidine

HRID 2303040Notes

Reaction equation

HRID 2303040 reaction equation
[CH2:1]1[O:12][C:11]2[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][C:3]=2[O:2]1.Cl[C:14]1[C:15]2[C:28]([CH3:29])=[CH:27][S:26][C:16]=2[N:17]=[C:18]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][N:21]=2)[N:19]=1>>[N:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[C:18]1[N:19]=[C:14]([NH:8][CH2:7][CH2:6][C:5]2[CH:9]=[CH:10][C:11]3[O:12][CH2:1][O:2][C:3]=3[CH:4]=2)[C:15]2[C:28]([CH3:29])=[CH:27][S:26][C:16]=2[N:17]=1

Participants

3

Reactant 2

HCID 738741,3-Benzodioxole-5-ethanamineHCID 184602084-Chloro-2-(pyridin-2-yl)-5-methyl-thieno-[2,3-d]-pyrimidine

Product 1

HCID 184601262-(Pyridin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-5-methyl-thieno-[2,3-d]-pyrimidine

Procedure

With the procedure of Example 1, the reaction of 3,4-methylenedioxyphenethylamine with 4-chloro-2-(pyridin-2-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-ac16d9142e964721be61aacc8c8e0fb5
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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