2-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amine → HCID 18459988, compound

HRID 2303121Notes

Reaction equation

HRID 2303121 reaction equation
[CH2:1]1[CH2:13][O:12][C:11]2[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][C:3]=2[O:2]1.Cl[C:15]1[C:16]2[CH:29]=[C:28]([CH2:30][CH3:31])[S:27][C:17]=2[N:18]=[C:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][N:22]=2)[N:20]=1>>[N:22]1[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=1[C:19]1[N:20]=[C:15]([NH:8][CH2:7][CH2:6][C:5]2[CH:9]=[CH:10][C:11]3[O:12][CH2:13][CH2:1][O:2][C:3]=3[CH:4]=2)[C:16]2[CH:29]=[C:28]([CH2:30][CH3:31])[S:27][C:17]=2[N:18]=1

Participants

3

Reactant 2

HCID 37470272-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amineHCID 184603294-Chloro-2-(pyridin-2-yl)-6-ethyl-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18459988HCID 18459988, compound

Procedure

With the procedure of Example 1, the reaction of 3,4-ethylenedioxyphenethylamine with 4-chloro-2-(pyridin-2-yl)-6-ethyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-2-yl)-4-(3,4-ethylenedioxyphenethylamino)-6-ethyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-ce6669e2653e4225a305169bf985ba33
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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