p-Fluorophenethylamine → HCID 18460011, compound

HRID 2303176Notes

Reaction equation

HRID 2303176 reaction equation
F[C:2]1[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][CH:3]=1.Cl[C:12]1[C:13]2[C:26]([CH3:27])=[CH:25][S:24][C:14]=2[N:15]=[C:16]([C:18]2[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=2)[N:17]=1>>[N:20]1[CH:21]=[CH:22][CH:23]=[C:18]([C:16]2[N:17]=[C:12]([NH:8][CH2:7][CH2:6][C:5]3[CH:9]=[CH:10][CH:2]=[CH:3][CH:4]=3)[C:13]3[C:26]([CH3:27])=[CH:25][S:24][C:14]=3[N:15]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 4653p-FluorophenethylamineHCID 184600144-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18460011HCID 18460011, compound

Procedure

With the procedure of Example 1, the reaction of 4-fluorophenethylamine with 4-chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-3-yl)-4-phenethylamino-5-methyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-2a3c3cb1c7b64bd3898fbe4f54f8492f
Source dataset
uspto-grants-2002_08
Patent number
US06432950B1

Reaction notes

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