Aluminium lithium hydride → HCID 22958917, compound

Participants

Reaction Steps

To a stirred suspension of the product of Step B (54 mg, 0.12 mmol) in 2 mL tetrahydrofuran at 0° C. was added lithium aluminum hydride (1.0M in tetrahydrofuran, 0.20 mL, 0.20 mmol). After refluxing for 2 hours, the reaction mixture was quenched with few drops of saturated sodium sulfate, and then solvent was removed in vacuo. Purification by prep-TLC afforded the title reduction product (21 mg, 41%).

Provenance & Evidence