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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303484Generated: November 2, 2026

Methanol → HCID 9955004, compound

https://huagongshe.com/reaction/2303484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodiumHCID 5360545—
ReactantHCID 10503986HCID 10503986—
SolventSodium HydroxideHCID 14798—
ProductHCID 9955004HCID 9955004415%

Reaction Steps

Using the procedure described in Example 2, Part E, 956 mg (2.1 mmol) of ([[3-(2-amino-1,2-dioxoethyl)-1-([1,1′-biphenyl]-3-ylmethyl)-2-methyl-1H-indol-4-yl]oxy]acetic acid methyl ester was hydrolyzed in 10 mL of 1N NaOH and 20 mL of MeOH to give 403 mg (415% yield) of [[3-(2-amino-1,2-dioxoethyl)-1-([1,1′-biphenyl]-3-ylmethyl)-2-methyl-1H-indol-4-yl]oxy]acetic acid, sodium silt, mp, >265° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06433001B1
Source datasetuspto-grants-2002_08
ORD IDord-fef19f80012a4a889e1a55da8f69b85e
Source noteuspto-grants-2002_08