HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 5-Nitroisophthaloyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 5-Nitroisophthalic acid | HCID 12069 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 5-Nitroisophthaloyl chloride | HCID 83451 | — |
Reaction Steps
To a stirred solution of 5-nitroisopthalic acid (10 grams) in methylene chloride (943 mL) was added oxalyl chloride (12.3 mL) and N,N-dimethylforamide (1 drop). The reaction mixture was stirred at room temperature overnight. Removal of the solvent in vacuo afforded 10.63 grams of the title compound. 1H NMR δ 9.17 (s, 2), 9.07 (s, 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06433009B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-527ebf16291f41e0af18ed2a8863b022 |
| Source note | uspto-grants-2002_08 |