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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303618Generated: November 2, 2026

Hydrochloric Acid → HCID 18187827, compound

https://huagongshe.com/reaction/2303618

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBenzonitrile, 4-bromo-HCID 12162—
Reactanttert-Butyl 4-(prop-2-en-1-yl)piperidine-1-carboxylateHCID 11117722—
ProductHCID 18187827HCID 18187827—

Reaction Steps

Starting with 4-(prop-2-en-1-yl)-1-t-butoxycarbonylpiperidine from Procedure 5, Step B (475 mg, 2.1 mmol) and using essentially the same methods as in Procedure 5, Step D, but substituting 4-bromobenzonitrile (382 mg, 2.1 mmol), the title compound (337 mg) was obtained as the hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432981B1
Source datasetuspto-grants-2002_08
ORD IDord-8080c2d7a7cb4f8ab40fe3dcc37d7552
Source noteuspto-grants-2002_08