HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,6-Dichlorobenzamido)pent-4-enoic acid methyl ester → HCID 57762596, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,6-Dichlorobenzamido)pent-4-enoic acid methyl ester | HCID 57762518 | — |
| Reactant | HCID 57762619 | HCID 57762619 | — |
| Product | HCID 57762596 | HCID 57762596 | 71.9% |
Reaction Steps
In the same manner as in Example 1, 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester (171 mg) was reacted with N-(4-iodophenyl)-N-propylpyrimidin-2-amine (192 mg) to obtain (E)-2-(2,6-dichlorobenzamido)-5-[4-(propyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid methyl ester (209 mg). Column chromatography (silica gel, eluent: cyclohexane/chloroform=4/1-3/1) was used for purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07566724B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-c6db002f2a1e47c9ba3e4da564785152 |
| Source note | uspto-grants-2009_07 |