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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 230370Erstellt: 25. Oktober 2026

Sodium Hydroxide → (s,e)-2-(2,6-Dichlorobenzamido)-5-[4-(4-methoxytetrahydropyran-4-yl)-phenyl]pent-4-enoic acid sodium salt

https://huagongshe.com/reaction/230370

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium HydroxideHCID 14798—
Edukt(S,E)-2-(2,6-dichlorobenzamido)-5-[4-(4-methoxytetrahydropyran-4-yl)-phenyl]pent-4-enoic acidHCID 11533406—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt(s,e)-2-(2,6-Dichlorobenzamido)-5-[4-(4-methoxytetrahydropyran-4-yl)-phenyl]pent-4-enoic acid sodium saltHCID 23664498—

Reaktionsschritte

To (S,E)-2-(2,6-dichlorobenzamido)-5-[4-(4-methoxytetrahydropyran-4-yl)-phenyl]pent-4-enoic acid (4.24 g), THF (8.86 ml) and 1N aqueous sodium hydroxide solution (8.86 ml) were added, and the resulting mixture was stirred at room temperature for 5 minutes. The reaction solution was concentrated to dryness to obtain (S,E)-2-(2,6-dichlorobenzamido)-5-[4-(4-methoxytetrahydropyran-4-yl)-phenyl]pent-4-enoic acid sodium salt (4.30 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07566724B2
Quelldatensatzuspto-grants-2009_07
ORD IDord-e4acbdc843924a55a0b2323c9d75be44
Quellennotizuspto-grants-2009_07