Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303729Generated: October 26, 2026

N-(2-acetyl-4,6-dimethylphenyl)-3-(((4-chloro-3-methyl-5-isoxazolyl)amino)sulfonyl)-2-thiophenecarboxamide → HCID 10206855, compound

https://huagongshe.com/reaction/2303729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-acetyl-4,6-dimethylphenyl)-3-(((4-chloro-3-methyl-5-isoxazolyl)amino)sulfonyl)-2-thiophenecarboxamideHCID 9934302—
ReactantCyclopropyl 2-amino-3,5-dimethylphenyl ketoneHCID 23445385—
ProductHCID 10206855HCID 10206855—

Reaction Steps

3-(((4-Chloro-3-methyl-5-isoxazolyl)amino)sulfonyl)-N-(2-(cyclopropylcarbonyl)-4,6-dimethylphenyl)-2-thiophenecarboxamide was synthesized in the same fashion as for N-(2-acetyl-4,6-dimethylphenyl)-3-(((4-chloro-3-methyl-5-isoxazolyl)amino)sulfonyl)-2-thiophenecarboxamide (Example 39) except that cyclopropyl 2-amino-3,5-dimethylphenyl ketone was used instead of 2′-amino-3′,5′-dimethylacetophenone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432994B1
Source datasetuspto-grants-2002_08
ORD IDord-f31dd0c057b744b08fd23ee835b27b19
Source noteuspto-grants-2002_08