HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18461311, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | 2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acid | HCID 11323485 | — |
| Reactant | HCID 18461288 | HCID 18461288 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18461311 | HCID 18461311 | 90.7% |
Reaction Steps
Using 0.96 g of t-butyl N-[2-amino-5-(4-methoxymethoxy-3,5-dimethylphenoxy)phenyl]-N-methylcarbamate, 0.84 g of 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid, 0.49 g of diethyl cyanophosphonate, 0.30 g of triethylamine and 60 ml of anhydrous tetrahydrofuran, reaction and purification were carried out in a similar manner to that described in Example (2-1), whereby 1.44 g of the desired compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-c037299a49c74818bb8f990daf1defab |
| Source note | uspto-grants-2002_08 |