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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303771Generated: October 31, 2026

Triethylamine → HCID 18461491, compound

https://huagongshe.com/reaction/2303771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461459HCID 18461459—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461491HCID 1846149148.6%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(pyridine-2-ylthio)phenyl]-N-methylcarbamate (0.78 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (1.06 g), diethyl cyanophosphonate (0.61 g), triethylamine (0.38 g) and anhydrous tetrahydrofuran (20 ml) and the reaction mixture was purified to give the desired product (0.68 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-bc2008bdc8c340aca26a4a755de519d5
Source noteuspto-grants-2002_08