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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303781Generated: November 2, 2026

Triethylamine → HCID 18461262, compound

https://huagongshe.com/reaction/2303781

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461279HCID 18461279—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461262HCID 1846126276.1%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(pyridin-3-yloxy)phenyl]-N-methylcarbamate (0.63 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.62 g), diethyl cyanophsphonate (0.36 g), triethylamine (0.22 g) and anhydrous tetrahydrofuran (15 ml) and the reaction mixture was purified to give the desired product (0.88 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-1bc4e84ab42447b0875ac5e132c0a2e5
Source noteuspto-grants-2002_08