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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303793Generated: November 2, 2026

Triethylamine → HCID 18461256, compound

https://huagongshe.com/reaction/2303793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461421HCID 18461421—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461256HCID 1846125693.8%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(3-t-butyl-4-hydroxyphenoxy)phenyl]-N-methylcarbamate (1.11 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.89 g), diethyl cyanophosphonate (0.52 g), triethylamine (0.32 g) and anhydrous tetrahydrofuran (20 ml) and the reaction mixture was purified to give the desired product (1.75 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-2ec20eb605b64762980bd81ca51721ef
Source noteuspto-grants-2002_08