HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18461314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | 2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acid | HCID 11323485 | — |
| Reactant | t-Butyl N-[2-amino-5-(2-t-butyl-4-hydroxyphenoxy)phenyl]-N-methylcarbamate | HCID 18461458 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18461314 | HCID 18461314 | 77.6% |
Reaction Steps
In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(2-t-butyl-4-hydroxyphenoxy)phenyl]-N-methyl-carbamate (0.95 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (0.76 g), diethyl cyanophosphonate (0.44 g), triethylamine (0.27 g) and anhydrous tetrahydrofuran (20 ml) and the reaction mixture was purified to give the desired product (1.24 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-f00e856ab75e4c03b2bb6412a2de95ea |
| Source note | uspto-grants-2002_08 |