HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18461303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | 2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acid | HCID 11323485 | — |
| Reactant | HCID 18461269 | HCID 18461269 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18461303 | HCID 18461303 | 89.2% |
Reaction Steps
In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(4-phenylphenoxy)phenyl]-N-methylcarbamate (1.60 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (1.26 g), diethyl cyanophosphonate (0.73 g), triethylamine (0.45 g) and anhydrous tetrahydrofuran (20 ml) and the reaction mixture was purified to give the desired product (2.39 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06432993B1 |
| Source dataset | uspto-grants-2002_08 |
| ORD ID | ord-61d98463ff714c64b68f17bb01810a98 |
| Source note | uspto-grants-2002_08 |