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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2303808Generated: November 4, 2026

Triethylamine → HCID 18461276, compound

https://huagongshe.com/reaction/2303808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
ReactantDiethyl cyanophosphonateHCID 76257—
Reactant2-(4-((2,4-Dioxothiazolidin-5-YL)methyl)phenoxy)acetic acidHCID 11323485—
ReactantHCID 18461380HCID 18461380—
SolventTetrahydrofuranHCID 8028—
ProductHCID 18461276HCID 1846127693.5%

Reaction Steps

In a similar manner to that described in Example (2-1), a reaction was carried out using t-butyl N-[2-amino-5-(4-methoxyphenoxy)phenyl]-N-methylcarbamate (2.0 g), 4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetic acid (2.0 g), diethyl cyanophosphonate (1.3 g), triethylamine (0.81 g) and anhydrous tetrahydrofuran (50 ml) and the reaction mixture was purified to give the desired product (3.3 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06432993B1
Source datasetuspto-grants-2002_08
ORD IDord-5b514d37b15849ccb5a181c23b52ea5c
Source noteuspto-grants-2002_08